SERPINB5 and lip and oral cavity carcinoma: We suggested that these genetic polymorphisms in exon region of Maspin, including G allele rs1455555, T allele rs2289519, and G allele rs2289520, could decrease or modulate Maspin protein function, which contributed to a more powerless cell-cell adhesion, and its interaction with alcohol consumption benefited oral cellular penetration to carcinogens and the development of oral cancer.