Increasing evidence has shown that epithelial-mesenchymal transition (EMT) is associated with cancer development and metastasis.1 Cancer cells with EMT phenotype change often involve in epithelial characteristics loss and mesenchymal properties acquisition, exhibiting enhanced motility, and invasive abilities.2 A typical characteristic of EMT process is the mesenchymal markers, such as vimentin increased, while epithelial markers decreased like E-cadherin, which induces disruption of cell-to-cell junctions. Here, CDH1 is linked to cancer.