LAMP2 and infection: As a control, either at 60 min or 24 h post infection in THP-1 or Vero cells, R. conorii maintain the morphology of intact bacteria, with no significant co-staining with LAMP-2 positive structures, and proliferate within these two cell types as depicted in an increase in rickettsial cells (Figure 6 and Supplementary Figure 5, Supplementary Movies 7, 8).