While we saw an increase in the number of CD3+CD8+ T lymphocytes and a higher CD8+/CD4+ ratio in the EoE-New/Active group, we did not appreciate a statistically significant increase in CD8+ or CD4+ populations suggesting a possible unexplored population of CD3+CD4−CD8− T cells accumulating in the EoE-New/Active patients (compared with EoE-Remission patients and controls) that remains to be explored (Table 3). Here, CD4 is linked to eosinophilic esophagitis.