Although we found that stimulated CD3+CD8+ T cells have increased IFN-γ in esophageal mucosal biopsies from EoE-New/Active (Figure 2b), IFN-γ was not detectable and not different among the study groups when we analyzed the supernatants (without stimulation) from explant tissue cultures (data not shown). This evidence concerns the gene IFNG and eosinophilic esophagitis.