Our third patient, a 42-year old male with stage IV BRAF V600 positive, Vemurafenib intolerant metastatic melanoma (patient 12), completed 16 weeks of the trial with stable disease but had persistently PET positive left axillary nodes which had not changed in size but did have some partial decrease in hypermetabolic activity while on the diet. The gene discussed is BRAF; the disease is metastatic melanoma.