In contrast, an increased or decreased risk of melanoma or non-melanoma cancer in patients with atopic dermatitis was confirmed by other researchers [3, 9]. Despite the high concentrations of IgE in this disease, atopic dermatitis is a more heterogenic disease than allergic rhinitis and also has non-allergic associations (e.g., autoimmunological and infectious diseases). Here, IGHE is linked to atopic eczema.