Most of the deleterious consequences of OSA, particularly those affecting the cardiovascular system, are exacerbated by oxidative stress and inflammatory cascades associated with the activation of the hypoxia-inducible factor 1 (HIF-1) signaling pathway (Peng et al., 2006; Yuan et al., 2008; Belaidi et al., 2009; He et al., 2014). This evidence concerns the gene HIF1A and obstructive sleep apnea syndrome.