PLB1 and Huntington disease: Thus in a similar fashion with the findings of Fonteh et al. the increased PLB1 phospholipase A2 expression levels in our HD blood samples could be indicative of perturbation of membrane structures with a concomitant disruption of cellular transport and clearances processes as well as a resulting inflammation overactivation (Stephenson et al. 1996; Sun et al. 2004).