There was no significant time by treatment interaction for exercise on circulating inflammatory biomarkers, CK-18, hsCRP, or the noninvasive markers of fibrosis (NAFLD fibrosis score, aspartate aminotransferase [AST]/alanine aminotransferase [ALT] ratio, and enhanced liver fibrosis test) (Table 4). The gene discussed is GPT; the disease is metabolic dysfunction-associated steatotic liver disease.