ZNF22 and neoplasm: Of the 14 candidate genes at the locus, we identified five as having significant cis eQTL in the cochlea (Table 4): Rassf4, March8, Zfp422, Olfr212, and Olfr215. Rassf4 may play a role in tumor suppression (Eckfeld et al. 2004), March8 induces the internalization of several membrane glycoproteins (Eyster et al. 2011), Zfp422 may play a role in osteogenic development (Ganss et al. 2002), and Olfr212 and Olfr215 are part of the olfactory receptor gene family (Zhang and Firestein 2002).