A role of CXCR4 and CXCL12 in EAE (Meiron et al., 2008; Kohler et al., 2008; McCandless et al., 2006) as well as in MS (Azin et al., 2012; Krumbholz et al., 2006) has been described. The gene discussed is CXCL12; the disease is myeloid sarcoma.