CTH and Sepsis: Alteration of the H2S/CSE signalling pathway is associated with various inflammatory diseases such as acute pancreatitis [4, 5], lipopolysaccharide (LPS)-induced endotoxemia [6, 7], severe burn injury [8], hind-paw edema [9], rheumatoid arthritis [10] as well as caecal-ligation and puncture (CLP)-induced sepsis [3, 11, 12].