These conditions induce 40–50% apoptotic cell death,29 resembling neuronal death in penumbra of a stroke.30 TTR KO neurons are more sensitive to this excitotoxic insult than WT neurons, showing less viable dendrites in MAP2 immunocytochemistry assays (Figure 4a) and western blot data (Figure 4b). The gene discussed is MAP2; the disease is stroke disorder.