LRP2 and Parkinson disease: These results resemble those observed in a kidney cell line, where NGAL (neutrophil gelatinase-associated lipocain) was able to reduce apoptosis in a hypoxia-reperfusion model, by regulating Bax and Bcl2 levels, in a megalin-dependent manner.46 The control of Bcl2 proteins has also been suggested as a strategy to treat neurodegenerative disorders, such as Parkinson.33