However, in the children who were deemed to have had high adherence to their intervention, waist circumference (p = 0.004), diastolic blood pressure (p = 0.007), mean arterial pressure (p = 0.005), fasting insulin (p = 0.013), and HOMA-IR (p = 0.016) were reduced in the high-protein compared with the low-protein diets, and serum insulin and insulin resistance were reduced in the lower-GI compared with the higher-GI diets (p = 0.04) [37]. The gene discussed is INS; the disease is Insulin resistance.