APAF1 and cancer: From 950 potential targets detected in the miRTarBase, we selected 11 based of their relevance to cancer and cell viability and apoptosis processes: CASP3, CCNE2, ABL2, APAF1, XIAP, BCL-2, PTEN, p53, E2F3, CDC25A, and BCL2L1 ligand (Table 1).