CML at 4–16 μmol/L and pentosidine at 2–16 μmol/L increased the production of ROS, TNF-α, IL-6 and TGF-β1 in A549 and Calu-6 cells (Table 3, p < 0.05). Here, IL6 is linked to chronic myelogenous leukemia, BCR-ABL1 positive.