FN1 and non-small cell lung carcinoma: The studies of Weng et al. [8] and Tsao et al. [9] revealed that the activation of MAPK and NF-κB pathways in non-small cell lung cancer (NSCLC) cells promoted the massive production of oxidative, inflammatory and angiogenic factors including reactive oxygen species (ROS), tumor necrosis factor (TNF)-α, intercellular adhesion molecule (ICAM)-1, transforming growth factor (TGF)-β1, vascular endothelial growth factor (VEGF), fibronectin and matrix metalloproteinases (MMPs).