For instance, wogonin, capsaicin, verrucarin A, curcumin, epigallocatechin gallate, and resveratrol, among others, have been reported to sensitize tumor cells to TRAIL-induced cell death, mostly through the cell surface receptor pathway via up-regulation of DR5/DR4 through c-FLIP [15–20]. This evidence concerns the gene TNFSF10 and neoplasm.