A recent study by Shang et al. 15 found that Tim‐3 expression in human OS tissues was association with the expression of EMT‐specific biomarkers, including vimentin, Slug, Snail, and Smad, suggest that TIM‐3 elicits tumor cells to acquire aggressive EMT features and may be involved in OS pathogenesis. This evidence concerns the gene HAVCR2 and neoplasm.