This wide predicted variation in the prescribing of DAAs was not seen in practice (Figures 1A,B), with the utilization of BCV and TVR (Figures 1A,B) appearing more similar compared with the appreciable differences in the utilization of other high priced medicines, e.g., TNF alpha inhibitors and those to treat patients with cancer or Type 2 diabetes (Hoebert et al., 2012; Jönsson et al., 2014; Putrik et al., 2014; Nolte and Corbett). This evidence concerns the gene TNF and cancer.