The pathways and genes that significantly changed were classified as follows: cancer pathways (EPAS1, CCND1, FGF13), myeloid leukemia pathways (ZBTB16, KIT, IL13), hematopoietic cell lineage pathways (EPOR, GYPA, CD36) and so on (Fig. 4). This evidence concerns the gene EPAS1 and myeloid leukemia.