PIK3CB and cancer: Among other cancer-related genes present on grey brocket Bs are: PIK3CB (phosphoinositide-3-kinase, catalytic, beta polypeptide) – an isoform of outer membrane kinase connected with DNA double-strand break repair and various types of cancer [51, 52]; CCND2 (cyclin D2), controlling G1/S transition in cell cycle known to be translocated in mantle-cell lymphoma [53]; OXSR1 (oxidative-stress responsive 1) – a serine/threonine kinase participating in stress response and cytoskeleton regulation, also was once identified as a weak candidate tumour suppressor [54].