UCHL1 and Parkinsonism: UCH-L1 is covalently modified by the endogenous parkinsonism-inducing dopamine derivative 1-(3′,4′-dihydroxybenzyl)-1,2,3,4-tetrahydroisoquinoline (3′,4′-DHBnTIQ), suggesting a possible role in the pathogenesis of idiopathic PD [102].