Hallmarks of immunogenic cell death [1, 3] include exposure of calreticulin on the tumor cell surface, which serves as an “eat-me” signal for dendritic cells [4] and macrophages [5], and HSP90 exposure, which facilitates dendritic cell-tumor cell adhesion and stimulates dendritic cell maturation [6]. The gene discussed is HSP90AA1; the disease is neoplasm.