Using this basic template of the study protocol of acute allergic asthma, migration of cells under no-disease condition (“clean” Rag2γc-/- where progenitors were killed off by lethal γ-irradiation and bone marrow cells from donors were allowed to repopulate all PLO and SLO) and under diseased condition where two genotype knockout mice were used and acute allergic asthma induced to track and study the various nuances of cell migration in the different PLO and SLO and their subsequent recruitment to the pulmonary tissue for orchestrating inflammation. Here, KCNMA1 is linked to allergic asthma.