The role of the 8q24 region on NSCL/P is still unclear but it might be involved in maintenance of an undifferentiated state in human acute myeloblastic leukemia cells (HL60) (Hirano et al., 2008), control of Myc expression (Uslu et al., 2014), or cranial facial enhancers (Attanasio et al., 2013). This evidence concerns the gene MYC and acute myeloid leukemia.