High resistin levels were found to be associated with increased cancer risk in the studies of breast cancer (OR = 1.19, 95% CI = 1.08-1.31), colorectal cancer (OR = 1.25, 95% CI = 1.02-1.53), Asia (OR = 1.66, 95% CI = 1.29-2.13), Europe (OR = 1.20, 95% CI = 1.07-1.33), ELISA (OR = 1.26, 95% CI = 1.15-1.38), retrospective studies (OR = 1.27, 95% CI = 1.15-1.40). The gene discussed is RETN; the disease is breast cancer.