We analyzed five different CRC cell lines: SW620 (KRAS G12V, BRAF wt), Colo-205 (KRAS wt, BRAF V600E), HT-29 (KRAS wt, BRAF V600E), HCT-15 (KRAS G13D, BRAF wt), and DLD-1 (KRAS G13D, BRAF wt), for TIMP-1 expression upon stimulation with EGF. This evidence concerns the gene TIMP1 and colorectal carcinoma.