These increased frequencies of CXCR3+ memory CD4 T cells in macaque LN versus reduced frequencies of CXCR3+ memory CD4 T cells in AGM LN during the acute phase of infection may be due to mobilization of these cells in the context of a strong pro-inflammatory context (CXCR3-ligands) in macaques. This evidence concerns the gene CXCR3 and infection.