The observation that exons in the 5’ region of GAK encoding the kinase and phosphatase/tensin domains of the protein are not differentially expressed in PD suggests that 5’ abbreviated transcripts (003, 007, and 014 through 023 in Fig 3), as well as the full-length transcripts (001 and 002 in Fig 3) of GAK may have little functional relevance to PD risk. The gene discussed is TNS1; the disease is Parkinson disease.