The statistically most significant eQTL in SCAN for our 206 SNPs is rs2395182 and the expression of eight HLA locus genes as well as other genes including RNASE2, and ZNF749. In our study, this SNP was associated with “rheumatoid arthritis and other inflammatory polyarthropathies” (ICD-9 code: 714). The gene discussed is ZNF749; the disease is arthropathy.