Looking at specific classes of antihypertensive drugs, CCBs were even more strongly associated with more aggressive tumors, multiplying by 2.7 the risk of tumors in stage III-IV (OR = 2.70, 95% CI = 1.23 to 5.95), non-ductal cancers (OR = 2.63, 95% CI = 1.27 to 5.43), and Erbb2+ cancer (OR = 2.52, 95% CI: 1.18 to 5.37). This evidence concerns the gene ERBB2 and cancer.