LMNA and laminopathy: Generally, the spatial reorganization of the genome is very similar between different laminopathy patients, regardless of the disease or mutation present (Meaburn et al., 2007; Mewborn et al., 2010), the exception being that chromosome 13 is more peripheral in patients with Δ303 or D596N LMNA mutations (Mewborn et al., 2010) and the spatial organization of the genome in asymptomatic laminopathy carriers is very similar to the laminopathy patients (Meaburn et al., 2007).