MKI67 and neoplasm: BON1RSUME-KD tumor samples exhibited significantly higher Ki67 proliferation index (12.70 ± 1.07% in BON1RSUME-KD tumors versus 10.15 ± 1.01% in BON1Scramble, P < 0.01) (Supplementary Figure 12), which is in line with the proliferation results in vitro (Supplementary Figure 11).