Similar to NUMB, the EMT negative regulators GATA3 and FOXA1 had significantly lower expression in the BLBC subtypes, ER-negative and higher histological grade breast cancer patients, while the EMT inducers FOXC1, FOXC2 and SNAI1 mimicked the expression profiles of Notch1 (Supplementary Figure S6). The gene discussed is NOTCH1; the disease is breast cancer.