There was no significant relationship between Panx3 expression and papilloma burden in female mice (p > 0.05, rho = −0.09; Additional file 2: Figure S5A) and Panx3 expression was not a significant predictor of carcinoma risk for female mice (p > 0.05; Additional file 2: Figure S5C). This evidence concerns the gene PANX3 and papilloma.