Furthermore, we confirmed that CCBE1 was co-localized with CD31 (a marker of vascular endothelial cells), but not with LYVE-1 (lymphatic vessel endothelial hyaluronan receptor 1, a marker of lymphatic endothelial cells), by IHC in serial sections of GIST tumor tissues (Fig. 6A). The gene discussed is LYVE1; the disease is gastrointestinal stromal tumor.