Compared with the control group, the VKC, SAC, and PAC groups had an increased expression of the ocular surface TSLP, IL-4 mRNA, IL-5 mRNA, and IL-13 mRNA; the differences were statistically significant (P < 0.05); the expression of TSLP, IL-4 mRNA, IL-5 mRNA, and IL-13 mRNA in the VKC group was significantly higher than in the SAC and PAC groups; the difference was statistically significant (P < 0.05). This evidence concerns the gene IL5 and gonorrhea.