In addition to conditioned medium from LPS-stimulated whole blood, we used plasma from sepsis patients to study the effect of cytokine adsorption on endothelial activation as described in “Materials and Methods.” For all plasma samples, IL-6 levels were >10,000 pg/ml at admission to the ICU (0 h) and at 1 h and >800 pg/ml at 24 h. This evidence concerns the gene IL6 and Sepsis.