CD63 and benign prostatic hyperplasia: In BPH and PCa patients, the mean plasma PSMA-positive EV concentration was 21.9 ng/mL and 51.5 ng/mL (p < 0.001) and the mean plasma CD63-positive EV concentration was 128 × 106 ng/mL and 145 × 106 ng/mL (p = 0.067), respectively.