Inaccordance with that results, proinflammatory profile also differed amongaPL(−) and aPL(+)-SLE patients, so that while in aPL(−)-SLEpatients cytokines such as IFNγ, IL-23, IL-1ß and TNFαwere more prevalent, in aPL-(+) SLE patients an increased expression of tPA,PAR-2 and TF was noticed (Fig. 4E,F). The gene discussed is TF; the disease is systemic lupus erythematosus.