The presentstudy further showed that aPL-IgG and anti-ds-DNA-IgG autoantibodies downregulatedin ECs all the miRNAs evaluated, also related to vascular dysfunction in the settingof APS and SLE, as demonstrated by the induced upregulation of MCP-1, TF, andVCAM-1, and the downregulation of eNOS in ECs. Here, FASLG is linked to systemic lupus erythematosus.