CBT-143-S-F6F7 also repressed the growth of subcutaneous Huh7 tumors in SCID mice (Fig. 2a) and reduced the expression of the cell cycle regulatory protein cyclin D1, cellular proliferation marker Ki-67, and endothelial marker CD31, according to immunohistochemical staining of subcutaneous HCC tumors (Fig. 3). Here, PECAM1 is linked to hepatocellular carcinoma.