Many factors, including vascular endothelial growth factor (VEGF), platelet-derived growth factor (PDGF), basic fibroblast growth factor (FGF), angiogenin, chemokine (C-X-C motif) ligand 16 (CXCL16), PDGF-AA, placental growth factor (PlGF), and urokinase-type plasminogen activator (uPA), contribute to tumor angiogenesis [15–20]. This evidence concerns the gene PLAU and neoplasm.