PLAU and neoplasm: Several research groups revealed insulin receptor (IR), insulin-like growth factor receptor 1 (IGF1R), epidermal growth factor receptor (EGFR), hepatocyte growth factor receptor (c-Met) and in particular the urokinase-type plasminogen activator (uPA) with its receptor (uPAR) to be overexpressed in many tumour entities including TNBC [3–9].