On the other hand, a statistically significant association between GST polymorphism and susceptibility to cRCC was found when the effect of GSTP1-variant genotype was analyzed in combination with the other three genotypes (GSTP1-variant and GSTM1-null OR = 11.23, 95%CI:2.62–48.08, p<0.001; GSTP1-variant and GSTA1low-activity OR = 4.93, 95%CI:1.48–16.43, p = 0.009; GSTP1-variant and GSTT1-active OR = 4.10, 95%CI:0.95–17.35, p = 0.05). The gene discussed is GSTP1; the disease is chromophobe renal cell carcinoma.