Namely, they were at increased risk of cRCC when compared to the normotensive GSTM1-active, GSTT1-null, GSTA1-active or GSTP1 wild-type individuals (OR = 6.01, 95%CI:2.48–14.52, p<0.001; OR = 3.27, 95%CI:1.20–8.91, p = 0.02; OR = 3.85, 95%CI:1.54–9.58, p = 0.004 and OR = 8.29, 95%CI:3.12–22.04, p<0.001 respectively, S1A Table). The gene discussed is GSTA1; the disease is chromophobe renal cell carcinoma.