For example, a recent study demonstrated that KIF14 contributes to chemoresistance in breast cancer by promoting AKT phosphorylation [50], and other research has shown that overexpression of kinesins (including KIFC3, KIFC1, KIF1A and KIF5A) mediates docetaxel resistance in breast cancer cells [47]. The gene discussed is KIFC3; the disease is breast carcinoma.