To shed light on how IL-7 and IFN-γ signalling in T cells affect T-cell proliferation, infiltration into tumours and functionality using our adoptive transfer system, we labelled purified total WT, Il7r−/− or Ifngr1−/− T cells (congenically marked by CD45.2) with CFSE before the adoptive transfer into CD45.1 mice, followed by MB49 tumour inoculation and combination therapy. Here, IFNGR1 is linked to neoplasm.