IL7R and neoplasm: As shown in Fig. 6c, although tumour growth appeared to be comparable among all cohorts in the early stage, combination therapy significantly reduced tumour volume in mice that were adoptively transferred with WT total T cells, but not in mice that received either Il7r−/− or Ifngr1−/− total T cells, pointing to an indispensable role of IL-7 and IFN-γ signalling in T cells in this process.