TFRC and microvillus inclusion disease: Previous studies on MVID patient biopsies and the recent analysis of the Myo5b knockout mouse have indicated that certain transporter proteins, such as CD36, Na+/K+ ATPase and transferrin receptor, are mislocalised in the absence of Myosin Vb function, indicative of a partial disruption of apico-basal polarity in mature enterocytes (Ameen and Salas, 2000, Carton-Garcia et al., 2015, Muller et al., 2008, Thoeni et al., 2014).