After adjustment for tumor size, hormone receptor status and neoadjuvant chemotherapy cycles, those who received paclitaxel with carboplatin/paclitaxel with cisplatin had a statistically significant higher rate of pCR Compared with patients who received cyclophosphamide, epirubicin and 5-fluorouracil [P = 0.003, odds ratio =27.696 (95 % CI: 3.131–245.030)]. This evidence concerns the gene NR4A1 and neoplasm.