One band was present selectively in ΔCDCP1 complexes and found to contain the adaptor protein p62/SQSTM1 that is involved in targeted autophagy and proteasomal degradation (reviewed in [46, 47]), and the matrix metalloproteinase MMP14 that promotes cancer metastasis by permitting cancer cell survival and proliferation through extracellular matrix degradation [48–50]. This evidence concerns the gene SQSTM1 and cancer.