STAT3 and prostate carcinoma: For example, baicalin and baicalein are extracted from Radix Scutellariae, which inhibits prostate cancer growth,[22] induces apoptosis,[23] and reduces free radicals.[24] Saikosaponin-d, extracted from Bupleuri Radix, inhibited human prostate cancer cells by inducing apoptosis and blocking the cell cycle.[25] 6-Shogaol, a component of ginger, restrained the growth of prostate cancer cells both in vitro and in vivo by inhibiting signal transducer and activator of transcription 3 (STAT3) and nuclear factor kappa-light-chain-enhancer of activated B cell (NF-κB) signaling.[26]