The human ortholog of lncRNA-mPvt1 is lncRNA-PVT1, which is significantly upregulated in HCC tissues.[27,36] LncRNA-PVT1 can promote HCC cell proliferation in vitro and in vivo, regulate the expression of cell cycle genes, predicts HCC recurrence following liver transplantation; moreover, it is involved in the pathway associated with the development of HCC.[27,36] The change in its expression level between sera from patients and healthy controls was consistent with the change between HCC tumor tissue and peritumoural tissue. The gene discussed is PVT1; the disease is neoplasm.