PVT1 and hepatocellular carcinoma: lncRNA-PVT1 has received much attention among oncogenic lncRNAs because it is involved in many types of tumor tissues, such as breast cancer, ovarian cancer, lung cancer, and gastric cancer.[31–34] This lncRNA is upregulated in gastric cancer, lung cancer, pancreatic cancer, and other cancers and is thought to play a role in drug resistance and tumor characteristics.[35] lncRNA-mPvt1 was first identified in mice, where it was upregulated in early liver tissues and HCC cell lines.